Healthcare Medical Devices Biotechnology

Sugar Spheres Market Report Cover

Sugar Spheres Market

Sugar Spheres Market Report Cover

Sugar Spheres Market Size, Share, Growth & Industry Analysis, By Product (Standard Spheres, Microspheres & Others), By Application (Tablet, Capsules & Others) and Regional Analysis, 2023-2030

Author : Mayank C.

Pages : 120

Base Year : 2022

Release : September 2023

Report ID: KR98

Sugar Spheres Market Size

The global Sugar Spheres Market size was valued at USD 164.2 million in 2022 and is projected to reach USD 278.2 million by 2030, growing at a CAGR of 7.0% from 2023 to 2030. Europe market size was valued at USD 62.6 million in 2022. The market is growing rapidly owing to the proliferating product demand across the pharmaceutical industry with applications in medicines. Technological advancements in pharmaceutical manufacturing and drug distribution systems are bolstering the market growth. The increasing focus of governments on expanding the product portfolio and fuelling the demand for the sugar sphere.

However, the high cost of raw materials leads to fluctuations in the overall production costs. Concerns regarding variation in size or shape can affect the flow properties of the spheres, affecting their effectiveness as excipients in drug delivery systems. Regulatory compliance is also a significant challenge in the production of sugar spheres for use in drug delivery systems. Manufacturers must invest in advanced manufacturing technologies and quality control processes to ensure consistency in the size and shape of the sugar balls.

Analyst’s Review

Sugar spheres are mainly used as inert cores in tablet and capsule formulations, especially in multi-particulate slow-release formulations. They provide the basis for coating the pharmaceutical products which is usually followed by a release modifying polymer coating. In addition, the multi-part drug delivery process is increasing as pharmaceutical companies seek to improve clinical efficacy. Sugar spheres are expected to be an important excipient in the production of solid drugs and are likely to be successfully used as a new development method.

Sugar granules have been widely used as functional excipients in the pharmaceutical industry and recent innovations in production technology have extended their applications to other sectors, such as the food & nutrition industry. The innovation is the development of organic sugar spheres and the development of sugar balls as building blocks for three-dimensional (3D) printing technology augments the market growth.

Market Definition

Sugar spheres are small, porous pellets used as pharmaceutical excipients in drug layering, sustained release, and extended-release dosage forms. The sugar spheres are first coated with a continuous release of the active ingredient and additives and are suitable, especially in combined medicines, because they are mostly found in depot tablets, other excipients can also be used in the mixture. These are water-soluble and hygroscopic, which often causes problems during coating. They are insoluble in water and are characterized by high sphericity and superior mechanical strength.

They are available in a variety of sizes and can be designed to release active ingredients at a controlled rate, offering great flexibility in formulation. They have excellent followability and shatter resistance, which makes them easy to handle and ideal for tableting and granulation processes. They are also relatively cheap and effective due to the availability of raw materials and have high porosity, which increases the absorption of active ingredients, improving bioavailability and solubility. In general, sugar spheres have several advantages that make them an attractive option as excipients in drug delivery systems, nutraceuticals, and food production.

Sugar Spheres Market Dynamics

Long-acting sugar spheres are a type of drug delivery system that uses miniature granules to gradually deliver a drug into the body over a long period. These dosage forms offer several advantages over traditional drug delivery methods, such as greater precision, better safety, and patient compliance. The manufacturing of sustained-release spheres can involve a variety of manufacturing processes, including extrusion spheronization, hot melt extrusion, and fluid bed coating. They are used to produce granules that maintain therapeutic levels of the drug in the body for long periods of time, resulting in sustained release of the drug.  Long-acting granules are primarily used to treat chronic conditions such as pain, diabetes, and hypertension. The effectiveness of these long-lasting granules depends on the properties of the drug to be administered, the composition of the pellet material, and the intended site for the drug to be administered.

Moreover, sustained sugar sphere formulations are becoming increasingly popular in the pharmaceutical industry due to their effectiveness and convenience. Pharmaceutical companies are constantly researching and improving sustained-release spheres to provide patients with better treatment options for a wide range of chronic conditions.

Sugar spheres offer unique advantages as functional excipients in the pharmaceutical, food & nutrition industry. However, the market faces several challenges related to alternative products that have been introduced in the market and its usability and interest in their use is constantly growing which restricts the market growth. They are insoluble in water and are characterized by high sphericity as well as superior mechanical strength. Manufacturers are seeking to differentiate their sugar spheres and offer added value to remain competitive in the market.

Segmentation Analysis

The global market is segmented based on product, application, and geography.

By Product

Based on the product, the sugar spheres market is classified into standard spheres and microspheres. The standard spheres segment held the majority share of 62.3% in 2022. The standard sugar spheres are available in different sizes and are designed to ensure a smooth and controlled release of the active ingredients. These are made from sucrose and cornstarch and are initially formed as small, irregular sugar crystals. These crystals are then turned into spherical granules in a process where the sugar crystals are layered with syrup and dried. Additionally, they have a high porosity level, which enhances the absorption of active substances and raises their bioavailability & solubility.

By Application

Based on application, the market is segmented into tablets and capsules. The tablets segment dominated the market in 2022 with a market share of 64.3%. In tablet formulations, sugar spheres are usually used as inert cores or fillers for active ingredients. The active ingredients are usually coated layer by layer on the surface of the sugar sphere to form long-acting or sustained-release tablets. Sugar spheres are often combined with other excipients, such as microcrystalline cellulose (MCC), to improve the tablet's mechanical properties and stability. In general, sugar spheres are an important component in many tablet formulations, especially those requiring continuous or sustained release.

Sugar Spheres Market Regional Analysis

Based on regional analysis, the global market is classified into North America, Europe, Asia Pacific, MEA, and Latin America.

Sugar Spheres Market Size & Share, By Region, 2023-2030

The sugar spheres market in Europe is the dominating region with a market share of 38.1% and was estimated at USD 62.6 million in 2022. The market in Europe is expected to grow significantly over the forecast period due to the increasing demand for drug delivery systems, rising healthcare costs, and expansion of the pharmaceutical industry. The growth of the market is also driven by the development of controlled-release sugar spheres and advances in manufacturing technology. Additionally, the demand for natural and organic sugar spheres is expected to increase as consumers are health conscious and examine products that do not contain synthetic ingredients. Stringent regulations on the use of the sugar sphere in drug delivery systems also provide many opportunities for market growth and innovation.

North America was valued at USD 46.0 million in 2022 and is slated to observe robust growth through 2030. The regional market growth is accelerated mainly due to the increase in chronic diseases in the population. Canada and Mexico also represent significant markets in North America, and the demand for sugar spheres in these countries is expected to increase in the coming years. The technological advancement in manufacturing and drug delivery systems, especially in the pharmaceutical industry has enabled the fabrication of more complex drug delivery systems with more controlled release properties. Growing demand for dietary supplements is also contributing to the growth of the sugar spheres market in North America. Nutritional companies use sugar granules as an ingredient in their products to improve their effectiveness and ensure optimal delivery.

Competitive Landscape

The sugar spheres market report will provide valuable insight with an emphasis on the fragmented nature of the global market. Prominent players are focusing on several key business strategies such as partnerships, mergers and acquisitions, product innovations, and joint ventures to expand their product portfolio and increase their respective market shares across different regions. Expansion & investments involve a range of strategic initiatives including investments in R&D activities, new manufacturing facilities, and supply chain optimization.

List of Key Companies in Sugar Spheres Market

  • Colorcon
  • Cornileus Pharmaceuticals (P) Ltd.
  • Dhanraj Sugars PVT. Ltd.
  • Emilio Castelli S.a.s. 
  • B. Sugars and Pharmaceuticals Limited
  • Meenaxy Pharma Private Limited (MPPL)
  • Nanjing Joyfulchem Co., Ltd.
  • Pharma Excipients International AG
  • Pharmatrans-Sanaq AG
  • Volza

The global Sugar Spheres Market is segmented as:

By Product

  • Standard Spheres
  • Microspheres

By Application

  • Tablet
  • Capsules

By Region

  • North America
    • U.S.
    • Canada
    • Mexico
  • Europe
    • France
    • UK
    • Spain
    • Germany
    • Italy
    • Russia
    • Rest of Europe
  • Asia Pacific
    • China
    • Japan
    • India
    • South Korea
    • Rest of Asia Pacific
  • Middle East & Africa
    • GCC
    • North Africa
    • South Africa
    • Rest of Middle East & Africa
  • Latin America
    • Brazil
    • Argentina
    • Rest of Latin America
  • Check Icon Additional Company Profiles
  • Check Icon Additional Countries
  • Check Icon Cross Segment Analysis
  • Check Icon Regional Market Dynamics
  • Check Icon Country-Level Trend Analysis
  • Check Icon Competitive Landscape Customization
  • Check Icon Extended Forecast Years
  • Check Icon Historical Data Up to 5 Years
Frequently Asked Questions (FAQ's)
The global market is projected to reach USD 278.2 million by 2030, growing at a CAGR of 7.0% from 2023 to 2030.
The global market was valued at USD 164.2 million in 2022.
The global market is growing rapidly owing to the proliferating demand across pharmaceutical industries with applications in medicines. The technological advancements in pharmaceutical manufacturing and drug distribution systems is expanding the market growth.
Top manufacturers of sugar spheres are Colorcon, Cornileus Pharmaceuticals (P) Ltd., Dhanraj Sugars PVT. Ltd., Emilio Castelli S.a.s., M. B. Sugars and Pharmaceuticals Limited, Meenaxy Pharma Private Limited (MPPL), Nanjing Joyfulchem Co., Ltd., Pharma Excipients International AG, Pharmatrans-Sanaq AG, Volza, and others.
Asia-Pacific is the fastest growing region with the CAGR of 9.0% in the forecasted period (2023-2030) with the market value forecasted to reach at USD 80.5 million.
By application, tablets will hold the maximum share in the sugar sphere market with the revenue value of USD 184.1 in 2030.
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