Real Time Polymerase Chain Reaction Systems Market

Real Time Polymerase Chain Reaction Systems Market Size

The global Real Time Polymerase Chain Reaction Systems Market size was valued at USD 4.93 billion in 2022 and is projected to reach USD 7.01 billion by 2030, growing at a CAGR of 4.57% from 2023 to 2030. The proliferating demand for real time polymerase chain reaction systems is driven by the growing use in life sciences and drug development, increasing government precision medicine initiatives across the world and surging investments by major players are some key factors fueling the growth of the market.

The escalating demand for automated instruments and high-throughput PCR systems, advances in the field of genomics, and number of scientific publications on various diseases are expected to drive the growth of the market. The increasing prevalence of cancer, availability of these tests at a lower cost compared to other PCR instruments, and rapid growth in the number of clinical trials are also fueling market expansion. However, the high cost associated with these devices, lack of skilled professionals, and quality issues may hinder the growth of the global real-time polymerase chain reaction systems market.

Analyst’s Review 

The surge in demand for real-time PCR systems for sample preparations and for accurate data analysis and interpretation at the time of high sample volumes and shorter timelines is also propelling the growth of market. The increasing spending on research & development, coupled with continuous demand for advanced real-time PCR systems for various research areas such as pathogen detection, genetic diseases, oncology, and pharmacogenomics, is also propelling the growth of real-time PCR systems market. The rising prevalence of chronic diseases increases the demand for advanced diagnostic technologies such as qPCR, which provides high sensitivity and specificity for disease detection and monitoring. With notable technological innovations in the field qPCR has become prominent tool for clinical laboratories and healthcare providers over the forecast period.

Market Definition

Real-time qPCRs offers sensitive and quantitative sample analysis and are detected in real time as the amplification reaction progresses. These methods are standard tools for quantifying target DNA sequences or monitoring gene expression. In recent years, real-time polymerase chain reaction (PCR) has become a powerful and widely used method for biological research due to its ability to detect and quantify very small specific nuclear sequences. Real-time PCR tests use specific pieces of DNA that are unique to the target to detect if the target is present in the sample. The advent of real-time PCR and real-time reverse transcription-PCR (real-time RT-PCR) has dramatically changed the field of gene expression measurement that collects data during the PCR process as it occurs, combining amplification and detection into a single step.

Market Dynamics

Infectious diseases are a major public health problem, affecting millions of people worldwide each year. Real-time polymerase chain reaction (PCR) systems are a powerful and highly sensitive diagnostic tool that can rapidly detect and identify the causes of infectious diseases. As the incidences of infectious diseases continues to increase, interest in the use of real-time PCR systems to improve the diagnosis, monitoring, and control of infectious diseases has increased. These systems are particularly well suited for rapid and accurate detection of infectious diseases because they can target specific nucleic acid sequences in a sample. According to the U.S. Department of Health & Human Services, in 2021 there were approximately 38.4 million people living with HIV in the world. Of these, 36.7 million were adults and 1.7 million were children (and 15-year-olds). In addition, real-time PCR can provide results quickly, which is much faster than traditional diagnostic methods such as culture-based methods.

The real-time polymerase chain reaction (qPCR) is a widely used technique in molecular biology that allows researchers to monitor and quantify a specific DNA molecule during the PCR amplification process. This powerful tool is used in many applications, including gene expression analysis, DNA sequencing, and pathogen detection. However, the high cost of real-time PCR systems is the primary factor that is hampering the growth of the market. One of the main challenges is the high cost of dPCR equipment and reagents, which can make it difficult for some laboratories to adopt this technology. These include the cost of reagents used to amplify and detect nucleic acids, and the cost of consumables. Despite the high cost of real-time PCR systems, these diagnostic tools remain an essential part of the diagnosis, monitoring, and control of infectious diseases. Efforts have been made to develop cost-effective real-time PCR systems, including inexpensive, portable systems that can be used in resource-limited settings. In addition, some organizations offer shared facilities and services to help reduce the cost of real-time PCR testing for research and clinical use. Although the efforts to decrease the cost of real-time PCR testing and expand the availability of these tools are essential to improving global health outcomes.

Segmentation Analysis

The global real time polymerase chain reaction systems market is segmented based on type, product, application, and geography.

By Type

Based on type, the market is bifurcated into specific detection and non-specific detection. The specific detection segment is the dominating segment with a valuation of USD 3.45 billion in 2022. The segment is growing rapidly due to several factors, such as the prevalence of chronic diseases, including cancer, infectious diseases, and diabetes. The specific test is a new and specialized approach that enables precise and highly accurate detection and quantification of nucleic acids.

By Product

Based on product, the real time polymerase chain reaction systems market is segmented into instruments, reagents & consumables, and software & services. The reagents & consumables segment is speculated to dominate the market over the forecast period owing to the rising demand for earlier detection of disease, and the surging number of significant companies manufacturing digital PCR consumables and reagents. The widespread use of consumables and reagents and expanding demand for healthcare, research, and other purposes are supporting the rise in segment share.

By Application

Based on application, the market is segmented into gene expression analysis, genotyping, GMO detection, and others. Gene expression analysis is expected to dominate the market with a CAGR of 3.93% over the estimated timeframe. These systems use specialized equipment and reagents to amplify and detect specific nucleic acid sequences in real time, providing quantitative information about the amount of nucleic acid present in the sample. Real-time PCR systems are particularly useful for monitoring the expression of specific genes and can provide insight into the regulation of gene expression under different conditions.  Real-time PCR systems have revolutionized gene expression analysis by providing a highly sensitive and specific means of detecting and quantifying gene expression.

Real Time Polymerase Chain Reaction Systems Market Regional Analysis

Based on regional analysis, the global real time polymerase chain reaction systems market is classified into North America, Europe, Asia Pacific, MEA and Latin America.

In North America, the real time polymerase chain reaction systems market is dominating and is growing with a market share of 43.12% in 2022. The market is growing rapidly owing to the increasing prevalence of infectious diseases and increasing number of clinical research studies in the North American region, are anticipated to propel market growth in the region. In addition, real-time PCR systems are an essential tool for gene expression analysis, providing quantitative insight into the regulation of gene expression under different conditions. Continued efforts to improve the technology and increase its availability and cost-effectiveness has expanded its application in various fields across the region. Furthermore, the pharmaceutical and healthcare industries' rising acceptance of technology innovations and increased research and development activities are foreseen to generate sizable growth potential for this market throughout the anticipated period.

Asia Pacific is the fastest growing market and is projected to depict a CAGR of 5.25% over 2023-2030. The regional market growth is attributed to the high adoption of technology supported by the introduction of products based on real-time PCR for screening and diagnosis of COVID-19 has expanded the growth at an exponential rate. The emergence of digital real-time polymerase chain reaction (dPCR) is growing rapidly across the APAC region as it offers accurate and precise measurement of the amount of nucleic acid present in the sample. The market has grown significantly in recent years, largely due to the growing demand for accurate and reliable nucleic acid quantification and analysis in various research and clinical applications.

Competitive Landscape

The global real time polymerase chain reaction systems industry study report will provide valuable insights with an emphasis on the fragmented nature of the global market. Prominent players are focusing on several key business strategies such as partnerships, mergers & acquisitions, product innovations, and joint ventures to expand their product portfolio and increase their respective market shares across different regions. Expansion & investments involve a range of strategic initiatives, including investments in R&D activities, new manufacturing facilities, and supply chain optimization.

List of Key Companies in Real Time Polymerase Chain Reaction Systems Market

• Abbott
• Agilent Technologies Inc
• Becton, Dickinson and Company
• Bio-Rad Laboratories, Inc. 
• Danaher Corporation
• Hoffmann-La Roche Ltd
• Lumex Instruments
• Merck KGaA
• Takara Bio Inc.
• Thermo Fisher Scientific Inc.
• BIOMÉRIEUX

Key Industry Developments

• May 2021 (Commercialization): Cipla Limited partnered with Ubio Biotechnology Systems Pvt. to commercialize ViraGen polymerase chain reaction (RT-PCR) testing kit for COVID-19 in India. Ltd. ViraGen is designed to qualitatively detect SARS-CoV-2 nucleic acid in upper and lower respiratory samples from individuals infected with COVID-19, which helped address current testing service and capacity challenges while enhancing the continued expansion of the diagnostic space.

The Global Real Time Polymerase Chain Reaction Systems Market is segmented as:

By Type

• Specific Detection
• Non-Specific Detection

By Product

• Instruments
• Reagents and Consumables
• Software and Services

By Application

• Gene Expression Analysis
• Genotyping
• GMO Detection
• Others

By Region

• North America
  • U.S.
  • Canada
  • Mexico
• Europe
  • France
  • UK
  • Spain
  • Germany
  • Italy
  • Russia
  • Rest of Europe
• Asia Pacific
  • China
  • Japan
  • India
  • South Korea
  • Rest of Asia Pacific
• Middle East & Africa
  • GCC
  • North Africa
  • South Africa
  • Rest of Middle East & Africa
• Latin America
  • Brazil
  • Argentina
  • Rest of Latin America