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Single-Use Bioprocessing Market Size, Share, Growth & Industry Analysis, By Product (Bioreactors, Tubing and Connectors, Pumps & Filters, Others), By Application (Upstream Processing, Downstream Processing, Others), By End-User (Biopharmaceutical Manufacturers, Research and Academic Institutions & Others), and Regional Analysis, 2024-2031
Pages: 190 | Base Year: 2023 | Release: February 2025 | Author: Sunanda G.
Single-use bioprocessing involves the use of disposable, pre-sterilized components and equipment in the manufacturing of biopharmaceuticals and biologics. These components, including bioreactors, filtration systems, bags, and tubing, are employed for a single production cycle and are discarded after use, eliminating the need for cleaning, sterilization, and validation of reusable equipment.
This approach offers benefits such as reduced risk of contamination, lower operational costs, faster setup times, and increased flexibility, making it an increasingly preferred in biomanufacturing processes, particularly for vaccines, cell and gene therapies, and monoclonal antibodies.
Global single-use bioprocessing market size was USD 18.65 billion in 2023, which is estimated to be valued at USD 21.01 billion in 2024 and reach USD 54.40 billion by 2031, growing at a CAGR of 14.56% from 2024 to 2031.
The growth of the market is driven by increasing demand for cost-effective and scalable production solutions, advancements in biopharmaceutical manufacturing, and the rising adoption of single-use technologies to minimize contamination risks and reduce operational costs. Additionally, strong government investments in biomanufacturing and the expanding biopharmaceutical sector further fuel market growth.
Major companies operating in the single-use bioprocessing market are DH Life Sciences, LLC, Merck KGaA, Thermo Fisher Scientific Inc., Saint-Gobain, Sartorius AG, 3M, Eaton, ALFA LAVAL, Lonza Group Ltd., Entegris, Parker Hannifin Corp., Avantor Inc., PBS Biotech Inc., Meissner Filtration Products, Eppendorf SE, and others.
The increasing demand for biopharmaceuticals due to the rising prevalence of chronic diseases is a significant factor contributing to the growth of the market.
This surge in cancer diagnoses highlights the urgent need for innovative treatments and therapies, creating a demand for single-use technologies and related products for drug development. The increasing focus on novel therapies for chronic conditions such as cancer is expected to further boost demand for single-use bioprocessing solutions.
Market Driver
"Increased Investment in Cell Therapy Research and Development"
The expansion of cell therapy production and investment is fueling the growth of the single-use bioprocessing market. Cell therapies, including CAR-T cell therapies and stem cell treatments, have gained significant traction, attracting substantial investment from both private and public sectors.
Companies are allocating considerable resources to expand their cell therapy production capabilities, often leveraging single-use bioprocessing technologies for cost-effective scalability and flexibility. This surge in investment is enhancing production capacity, leading to their widespread adoption in the cell therapy manufacturing.
Market Challenge
"High Initial Investment in Single-Use Bioprocessing Systems"
A critical challenge impacting the growth of the single-use bioprocessing industry is the high initial investment required for these systems. The upfront costs can be prohibitive, particularly for smaller companies or those with limited financial resources.
To overcome this challenge, several companies are opting for a gradual adoption strategy, integrating single-use technologies in stages to manage capital expenses more effectively.
Additionally, efforts are being made to enhance the cost-efficiency of these systems, along with offering more flexible financing options, thereby reducing the financial strain and promoting broader adoption across the industry.
Market Trend
"Adoption of Single-Use Technologies to Mitigate Cross-Contamination"
The increasing adoption of single-use technologies by biopharmaceutical companies to minimize the risk of cross-contamination is expected to significantly fuel the growth of the single-use bioprocessing market.
This rapid adoption enables manufacturers to quickly adjust to evolving market demands and production schedules, boosting operational efficiency.
Segmentation |
Details |
By Product |
Bioreactors (Single-use stirred tank bioreactors (SUBs), Single-use wave bioreactors, Single-use perfusion bioreactors, Others), Tubing and Connectors (Silicone tubing, Fluoropolymer tubing, Connectors), Bags and Bottles (Harvest bags, Buffer bags, Storage bags), Pumps & Filters (Depth filters, Membrane filters, Peristaltic pumps, Diaphragm pumps, Others), Others |
By Application |
Upstream Processing (Cell culture, Fermentation, Cell growth, Cell Expansion), Downstream Processing (Cell harvesting, Cell lysis, Protein Purification), Others |
By End-User |
Biopharmaceutical Manufacturers, Research and Academic Institutions, |
By Region |
North America: U.S., Canada, Mexico |
Europe: France, UK, Spain, Germany, Italy, Russia, Rest of Europe |
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Asia-Pacific: China, Japan, India, Australia, ASEAN, South Korea, Rest of Asia-Pacific |
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Middle East & Africa: Turkey, UAE, Saudi Arabia, South Africa, Rest of Middle East & Africa |
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South America: Brazil, Argentina, Rest of South America |
Market Segmentation:
Based on region, the global market has been classified into North America, Europe, Asia Pacific, Middle East & Africa, and Latin America.
The North America single-use bioprocessing market captured a share of 36.74% in 2023, valued at USD 6.85 billion. This is largely attributed to the increasing research and development spending, the presence of large manufacturing units, and the growing preference for disposable products.
The region’s well-established biopharmaceutical sector, along with the widespread availability of single-use assembly products from regional market leaders further supports this expansion.
Additionally, increased investment by the U.S. government in the bioprocessing industry, the presence of prominent industry players, and a rising number of product developments are expected to support regional market growth.
This investment is poised to strengthen the country's pandemic response and life sciences innovation, boosting demand for single-use technologies. By eliminating the need for expensive stainless-steel equipment and cleaning procedures, these technologies are expected to support regional market growth in the region.
Asia Pacific single-use bioprocessing industry is set to grow at a robust CAGR of 16.46% over the forecast period. This growth is propelled by rapid advancements in biomanufacturing technologies, increasing demand for biopharmaceuticals due to rising chronic disease prevalence, and strong government support for the life sciences and biopharmaceutical sectors.
Additionally, the expansion of healthcare infrastructure and the growing adoption of cost-effective, scalable production solutions among emerging markets in the region further contribute to domestic market growth.
The single-use bioprocessing industry is characterized by a number of participants, including both established corporations and established players. Market participants are adopting strategies such as product innovation and increased investment in research and development (R&D) to expand their market base.
By developing advanced and more efficient single-use systems, these companies aim to meet the growing demand for cost-effective, scalable biomanufacturing solutions.
Additionally, R&D initiatives focus on improving product performance, enhancing user experience, and addressing industry-specific challenges, which helps companies gain a competitive edge and contributes significantly to the market growth.
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