Healthcare Medical Devices Biotechnology

Gene Synthesis Market Report Cover

Gene Synthesis Market

Gene Synthesis Market Report Cover

Gene Synthesis Market Size, Share, Growth & Industry Analysis, By Type (Gene Synthesis Products, Gene Synthesis Services), By Application (Gene Editing, Vaccine Development, Functional Genomics, Protein Production, Synthetic Biology), By End-User (Biopharmaceutical Companies, Academic and Research Institutes) and Regional Analysis, 2023-2030

Author : Omkar R.

Pages : 120

Base Year : 2022

Release : December 2023

Report ID: KR293

Gene Synthesis Market Size

The global Gene Synthesis Market size was valued at USD 2.24 billion in 2022 and is projected to reach USD 11.12 billion by 2030, growing at a CAGR of 22.17% from 2023 to 2030. In the scope of work, the report includes products offered by companies such as Thermo Fisher Scientific Inc., GenScript Biotech Corporation, Twist Bioscience Corporation, Integrated DNA Technologies, Inc., Eurofins Scientific SE, Bioneer Corporation, OriGene Technologies, Inc., Bio Basic Inc., Merck KGaA, ATUM and others.

The gene synthesis market is set to experience significant growth over the forecast period driven by various factors. Advancements in biotechnology and synthetic biology have paved the way for innovative applications of gene synthesis, such as gene editing for disease treatments and sustainable agriculture. Furthermore, the decreasing cost and increased accessibility of gene synthesis technologies have made the field more accessible to researchers, startups, and industries. The demand for personalized medicine and the rapid development of vaccines, particularly in response to emerging infectious diseases, have further contributed to market growth.

Customized DNA sequences are crucial for tailoring treatments and vaccines to specific individuals or pathogens. Additionally, the expanding scope of synthetic biology has opened up new possibilities for creating synthetic organisms and materials. Moreover, gene synthesis is expected to play a pivotal role in gene therapy, regenerative medicine, and industrial biotechnology, offering significant opportunities for scientific advancements and economic growth as the technology matures and regulatory frameworks evolve.

Analyst’s Review on Gene Synthesis Market

Between 2023 and 2030, the gene synthesis market is expected to witness significant trends. Automation and high-throughput methods are likely to revolutionize the market dynamics, making gene synthesis faster, more cost-effective, and accessible to a wider audience. This will result in a greater demand for custom DNA sequences, thereby driving market growth.

Additionally, machine learning and artificial intelligence will be pivotal in the design and optimization of sequences, improving the efficiency and accuracy of gene synthesis. These AI-driven design tools will enable researchers to create more intricate and functional DNA sequences for various applications.

However, the market faces challenges in its growth trajectory due to ethical and safety concerns regarding the potential misuse of synthetic DNA and the creation of harmful organisms. Regulatory bodies must adapt to ensure the responsible use of gene synthesis technologies while fostering innovation. Overall, the gene synthesis market is poised to observe dynamic growth, driven by technological advancements and diverse applications across multiple industries.

Market Definition

Gene synthesis is the artificial construction of DNA sequences, where nucleotides are assembled in a specific order to create customized DNA. This process has diverse applications in various fields. In gene editing, customized DNA sequences are crucial for precise modifications of genes, offering potential treatments for genetic disorders.

Gene synthesis also enables rapid design and production of DNA constructs for vaccine candidates, aiding in the development of tailored vaccines during public health emergencies. Researchers use synthesized DNA to study gene function and regulation in functional genomics, investigating how genes affect cellular processes and disease pathways. Gene synthesis is also instrumental in producing recombinant proteins for pharmaceuticals, research, and industrial applications.

In synthetic biology, gene synthesis is used to engineer organisms with novel functions or traits, benefiting biofuel production, bioremediation, and bio-based materials. Gene synthesis services cater to academic institutions and biotech companies, providing custom DNA sequences for research and development projects. Gene synthesis is a versatile technology that addresses various scientific and industrial challenges.

Market Dynamics

The increasing demand for personalized medicine is one of the main factors driving gene synthesis market growth. As the understanding of genetics and genomics advances, there is a growing requirement for customized DNA sequences to develop treatments tailored to individual patients. Gene synthesis facilitates the creation of therapies tailored to individual patients, contributing to the progress of precision medicine.

However, the gene synthesis market faces a significant challenge in terms of ethical and safety concerns associated with synthetic biology. The accessibility of this technology raises concerns about the potential misuse of synthesized DNA for harmful purposes, including the creation of dangerous pathogens. Balancing the promotion of innovation with ensuring responsible use presents a complex challenge for both industry stakeholders and regulatory authorities.

One major growth opportunity in the gene synthesis space is the field of regenerative medicine. As this field progresses, there is a growing demand for customized DNA constructs for tissue engineering and regenerative therapies. Gene synthesis can play a crucial role in creating tissues and organs that are specific to each patient, which has the potential to revolutionize the treatment of injuries and degenerative diseases. This opportunity has the potential to improve patient outcomes and it represents a significant market segment for gene synthesis providers.

Segmentation Analysis

The global gene synthesis market is segmented based on type, application, end-user, and geography.

By Type

Based on type, the market is bifurcated into gene synthesis products and gene synthesis services. The gene synthesis services segment outperformed the gene synthesis products segment in 2022, generating the highest valuation. This signifies the increasing demand for specialized gene synthesis solutions, highlighting the market's focus on custom DNA sequences and personalized genetic constructs to meet various research and biotechnology requirements.

By Application

Based on application, the market is segmented into gene editing, vaccine development, functional genomics, protein production, synthetic biology, academic and industrial research, and others. The gene editing segment is poised to record significant growth with the highest CAGR projected for the forecast period. This growth is driven by the transformative effects of gene editing technologies, particularly CRISPR-Cas9, which have revolutionized precise genetic modifications for research and therapeutic purposes.

As the demand for targeted gene alterations increases in sectors such as healthcare, agriculture, and biotechnology, the gene editing segment is expected to contribute substantially to shaping the future of genetic engineering.

By End-User

Based on end-user, the market is categorized into biopharmaceutical companies, academic and research institutes, contract research organizations (CROs), gene editing companies, and others. The biopharmaceutical companies segment dominated the global gene synthesis market in 2022 driven by the extensive use of gene synthesis technology.

The surging adoption of gene synthesis is fostered by the requirement for custom DNA constructs in areas such as drug discovery, vaccine development, and the production of biopharmaceutical products. By harnessing synthetic biology and genetic engineering, these companies have taken the lead in driving innovation, advancing therapeutic research, and shaping the modern medical landscape.

Gene Synthesis Market Regional Analysis

Based on regional analysis, the global gene synthesis market is classified into North America, Europe, Asia Pacific, MEA, and Latin America.

North America dominated the gene synthesis market in 2022 due to various factors. The United States, in particular, has thriving biotechnology and life sciences industries, with numerous research institutions, biotech startups, and established companies leading innovation in gene synthesis. The region also benefits from a supportive regulatory environment and a strong network of investors and venture capitalists willing to fund biotech ventures.

North America's leadership in gene synthesis is further reinforced by its significant role in gene editing research, pharmaceutical development, and rapid response to emerging infectious diseases through vaccine development, all of which heavily rely on custom DNA sequences synthesized in the region.

Asia-Pacific is projected to be the fastest-growing region in the gene synthesis market with the highest CAGR over the assessment period. Countries in Asia-Pacific, particularly China, and India, are investing heavily in biotechnology and synthetic biology research, fostering innovation and increasing the demand for gene synthesis services.

Moreover, the growing population and rising healthcare needs in the region are driving the demand for personalized medicine and gene-based therapies, which is further contributing to the expansion of the gene synthesis market. Additionally, the growth of the pharmaceutical and biotechnology industries in Asia-Pacific plays a pivotal role in the rapid expansion of the gene synthesis market in the region.

Competitive Landscape

The global gene synthesis market report will provide valuable insight with an emphasis on the fragmented nature of the global industry. Prominent players are focusing on several key business strategies such as partnerships, mergers and acquisitions, product innovations, and joint ventures to expand their product portfolio and increase their market shares across different regions. Expansion & investments involve a range of strategic initiatives including investments in R&D activities, new manufacturing facilities, and supply chain optimization which could pose new opportunities for the market.

List of Key Companies in Gene Synthesis Market

  • Thermo Fisher Scientific Inc.
  • GenScript Biotech Corporation
  • Twist Bioscience Corporation
  • Integrated DNA Technologies, Inc.
  • Eurofins Scientific SE
  • Bioneer Corporation
  • OriGene Technologies, Inc.
  • Bio Basic Inc.
  • Merck KGaA
  • ATUM

Key Industry Developments

  • July 2023 (Partnership, and Product Launch): Eurofins Genomics and Blue Heron, both leading providers of genomics solutions, announced the launch of an in vitro transcription mRNA synthesis service. This service was intended to meet the growing demand for high-quality mRNA molecules used in gene therapy, vaccine development, and research applications. The collaboration between Eurofins Genomics and Blue Heron offers researchers a reliable and efficient solution for obtaining custom-made mRNA molecules for their projects.
  • January 2023 (Acquisition): Moderna, Inc., a biotechnology company specializing in mRNA therapeutics, announced its acquisition of OriCiro Genomics. This acquisition marked Moderna's first purchase of another company and further expanded its capabilities in the field of genetic research and development.

The global Gene Synthesis Market is segmented as:

By Type

  • Gene Synthesis Products
  • Gene Synthesis Services

By Application

  • Gene Editing
  • Vaccine Development
  • Functional Genomics
  • Protein Production
  • Synthetic Biology
  • Academic and Industrial Research
  • Others

By End-User

  • Biopharmaceutical Companies
  • Academic and Research Institutes
  • Contract Research Organizations (CROs)
  • Gene Editing Companies
  • Other

By Region

  • North America
    • U.S.
    • Canada
    • Mexico
  • Europe
    • France
    • U.K.
    • Spain
    • Germany
    • Italy
    • Russia
    • Rest of Europe
  • Asia-Pacific
    • China
    • Japan
    • India
    • South Korea
    • Rest of Asia Pacific
  • Middle East & Africa
    • GCC
    • North Africa
    • South Africa
    • Rest of Middle East & Africa
  • Latin America
    • Brazil
    • Argentina
    • Rest of Latin America
  • Check Icon Additional Company Profiles
  • Check Icon Additional Countries
  • Check Icon Cross Segment Analysis
  • Check Icon Regional Market Dynamics
  • Check Icon Country-Level Trend Analysis
  • Check Icon Competitive Landscape Customization
  • Check Icon Extended Forecast Years
  • Check Icon Historical Data Up to 5 Years
Frequently Asked Questions (FAQ's)
The global market is projected to reach USD 11.12 billion by 2030, growing at a CAGR of 22.17% from 2023 to 2030.
The global market was valued at USD 2.24 billion in 2022.
Rapid advancements in gene editing technologies and the increasing demand for personalized medicine are driving the growth of the gene synthesis market.
Top manufacturers of gene synthesis are Thermo Fisher Scientific Inc., GenScript Biotech Corporation, Twist Bioscience Corporation, Integrated DNA Technologies, Inc., Eurofins Scientific SE, Bioneer Corporation, OriGene Technologies, Inc., Bio Basic Inc., Merck KGaA, ATUM, and others.
Asia-Pacific is the fastest growing region with the highest CAGR in the forecasted period (2023-2030).
By type, gene synthesis services segment will hold the maximum share in the gene synthesis market in 2030.
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